Keio University Human Biology-Microbiome-Quantum Research Center (WPI-Bio2Q) will hold a seminar as follows.
This is an event for faculty, students, and staff of Keio University.

The human microbiome is an important modifier of health risks. Specific gut microbiome biomarkers, including bacterial species and various proteins or metabolites they produce, offer a compelling opportunity to support early life development, improve cardiometabolic health or promote healthy aging. In this talk, I will discuss identification of Eubacterium and Oscillibacter spp. that modify sterols through glycosylation and dehydrogenation, as well as a discovery of novel protease allergens encoded in the gut microbiome. These examples will demonstrate the value of large human cohorts, multi-omics data integration and AI advancement for modelling the language of proteins and their structures. Finally, I will describe the translational efforts in Novonesis to convert microbiome discoveries into products available to everyone with an example of early life interventions with Bifidobacterium spp.