PUBLICATIONS

Butyrate Modulates CXCR4 Expression and IL-5-Induced Inflammatory Responses in Human Eosinophils

Matsuyama E, Miyata J, Kawashima Y, Konno R, Hasegawa Y, Mizobe M, Fukasawa Y, Onozato R, Otsu Y, Sunata K, Sasaki H, Masaki K, Kabata H, Arita M, Fukunaga K. Allergy. 2026 October 8; PMID: 42850681. doi:10.1111/all.70540

Lysophospholipase PNPLA7 is a critical checkpoint of phosphatidylcholine catabolism and turnover for skeletal muscle homeostasis

Matsumoto S, Seo H, Taketomi Y, Higashi T, Nagasaki Y, Sato H, Kawaguchi M, Nishito Y, Park J, Mizuguchi K, Hosomi K, Kunisawa J, Saito K, Kato K, Soga T, Hirabayashi T, Ogawa S, Murakami M. Cell Rep. 2026 September 30; PMID: 42815479. doi:10.1016/j.celrep.2026.118003

Loss of Newborn Neuron Function Promotes Aβ Accumulation in an Alzheimer's Disease Mouse Model

Tamura R, Kawabata R, Lei C, Li H, Hayashi D, Seki M, Suzuki Y, Hisatsune T. Aging Dis. 2026 September 24; PMID: 42809425. doi:10.14336/AD.2026.0713

The Gibbs free energy landscape based on liver metabolome revealed thermodynamic robustness against fasting and obesity

Abekawa T, Ohno S, Hirayama A, Soga T, Kuroda S. iScience. 2026 September 24; 29(10):117618. doi:10.1016/j.isci.2026.117618

Distinct metabolomic signatures of SGLT2 inhibitor vs. sulfonylurea in a paired human liver biopsy study

Takeshita Y, Oo HK, Nakano Y, Ueno A, Oishi M, Tsujiguchi H, Soga T, Yamashita T, Honda M, Takamura T. Biochem Biophys Rep. 2026 September 14; 48:102784. doi:10.1016/j.bbrep.2026.102784

Engineering Piezo1-Mediated Calcium Signalling for Enhanced Extracellular Vesicle Biogenesis and Cargo Loading

Saleh NA, Shafiq R, Cicerone AP, Kilangodi S, Hartwig H, Mias GI, Lu G, Huh JR, Li W, Deng CX, Kanada M. J Extracell Biol. 2026 August 29; 5(9):e70182. doi:10.1002/jex2.70182

Aberrant alternative splicing memorized in adipose tissue macrophages impedes efferocytosis during postobesity weight loss

Miyazaki T, Shiraishi A, Sugiura Y, Shiozawa E, Mizuno S, Yamaguchi M, Nakano R, Uchida Y, Yoshikawa A, Hosonuma M, Haraguchi S, Morito D, Aoki T, Yamochi T, Kamijo S, Izumizaki M, Shitara H, Taketomi Y, Takahashi S, Satake H. Sci Transl Med. 2026 August 26; 18(864):eadv0221. doi:10.1126/scitranslmed.adv0221

Defined human Clostridia consortia reverse colitis via dual effects of tryptophan metabolites on microbiota and immunity

Oka A, Bongers G, Mishima Y, Baltus AJ, Gray SM, Liu B, Herzog JW, Benedetto JR, Fan TJ, Jang J, Awoniyi M, Rousta E, Hao LY, Gharaibeh RZ, Fodor AA, Ohkusa T, Atarashi K, Fukuda S, Honda K, San Mateo LR, Sartor RB. Cell Host Microbe. 2026 August 26; 9;34(9):1746-1763.e15. doi:10.1016/j.chom.2026.08.003

Integrative Omics of Eosinophils in Asthma and COPD: Deciphering Molecular Signatures for Targeted Therapy

Miyata J, Sunata K, Sasaki H, Chubachi S, Hasegawa Y, Kawashima Y, Arita M, Fukunaga K. Mol Diagn Ther. 2026 August 22; PMID: 42631787. doi:10.1007/s40291-026-00877-y

Burden and genomic characterisation of Shigella-associated diarrhoea in children younger than 5 years in Lusaka, Zambia: a prospective cohort study

Chibuye M, Harris VC, Brizuela J, Bosomprah S, Simuyandi M, Mwape K, Silwamba S, Liswaniso F, Chibesa K, Miti S, Piedade G, Luchen CC, Chisenga CC, Mende DR, Schultsz C, Chilengi R. Lancet Microbe. 2026 August 19; 7(10):101408. doi:10.1016/j.lanmic.2026.101408

rs57494551 increases CXCR5 expression and IgM(+) CXCR5(+) B-cell infiltration in the portal area of primary biliary cholangitis

Hitomi Y, Aiba Y, Ueno K, Takahashi H, Kono M, Sugi K, Teraoka Y, Takaki S, Naganuma A, Kojima M, Nishida N, Kawai Y, Kawashima M, Khor SS, Yasunami M, Komori A, Shimoda S, Ishigaki K, Nagasaki M, Tokunaga K, Nakamura M. J Gastroenterol. 2026 August 10; PMID: 42573624. doi:10.1007/s00535-026-02493-3

Blocking L-carnitine synthesis by meldonium prolongs the survival in mice with pancreatic cancer

Sano M, Ijichi H, Tabata S, Hirayama A, Shimma S, Masugi Y, Ichimaru Y, Kim J, Kimura G, Miyabayashi K, Takahashi R, Hatakeyama H, Suzuki T, Masamune A, Soga T, Fujishiro M. iScience. 2026 August 6; 29(8):117071.. doi:10.1016/j.isci.2026.117071.

Subclinical cholestasis is a hallmark of gut dysbiosis causing resistance to cancer immunotherapy

Mallard de La Varende AL, Tian AL, Thomas S, Lahmar I, Messaoudene M, Li S, Motiño O, Guillaume-Dit-Taunière H, Iebba V, Hurtado Y, Pham TN, Thélémaque C, Araujo-Voces M, Suissa D, Ly P, Reich E, Vitali G, Arlunno BT, Durand S, Aprahamian F, Leduc M, Forveille S, Kepp O, de la Calle-Fabregat C, Schippers A, Wagner N, Fournier PE, Mallard de La Varende AL, Tian AL, Thomas S, Lahmar I, Messaoudene M, Li S, Motiño O, Guillaume-Dit-Taunière H, Iebba V, Hurtado Y, Pham TN, Thélémaque C, Araujo-Voces M, Suissa D, Ly P, Reich E, Vitali G, Arlunno BT, Durand S, Aprahamian F, Leduc M, Forveille S, Kepp O, de la Calle-Fabregat C, Schippers A, Wagner N, Fournier PE, Honda K, Marmorino F, Cremolini C, Maleki Vareki S, Lenehan JG, Marabelle A, Danlos FX, Deligne M, Truntzer C, Ghiringhelli F, Ree AH, Bousquet PA, Meltzer S, Ginhoux F, Rummel D, Fu Y, Quinn RA, Alves Costa Silva C, Iacovelli R, Ciccarese C, Porcari S, Elkrief A, Routy B, Ianiro G, Derosa L, Kroemer G, Fidelle M, Zitvogel L. Honda K, Marmorino F, Cremolini C, Maleki Vareki S, Lenehan JG, Marabelle A, Danlos FX, Deligne M, Truntzer C, Ghiringhelli F, Ree AH, Bousquet PA, Meltzer S, Ginhoux F, Rummel D, Fu Y, Quinn RA, Alves Costa Silva C, Iacovelli R, Ciccarese C, Porcari S, Elkrief A, Routy B, Ianiro G, Derosa L, Kroemer G, Fidelle M, Zitvogel L. Cancer Cell. 2026 July 29; 44(8):1653-1671.e16. doi:10.1016/j.ccell.2026.06.022

Nicotinic Acid Restriction Enhances the Therapeutic Benefit of NAMPT Inhibition in Small-Cell Lung Cancer Models

Tsurumi K, Nomura M, Ouchi M, Yagishita S, Kikuchi N, Sato T, Morita M, Yamashita Y, Hayashi K, Soga T, Hamada A, Fukuhara T, Tanuma N. Cancer Sci. 2026 July 28; PMID: 42521252. doi:10.1111/cas.70486

Accurate, sensitive, and efficient chromatin accessibility quantification at target loci using UNIChro-seq

Kono M, Hatano H, Asahara K, Nakano M, Bagherzadeh R, Kawashima T, Arakawa T, Sato M, Inokuchi H, Nishino T, Itamiya T, Takahashi H, Natsumoto B, Suzuki A, Yamamoto K, Ishigaki K. Nat Commun. 2026 July 20; 17(1):8807. doi:10.1038/s41467-026-75767-2