Keio University Human Biology-Microbiome-Quantum Research Center (WPI-Bio2Q) held a seminar as follows.

Date：17:00 -18:00, September 14, 2026

Venue：2F Meeting room, Center for Integrated Medical Research, Shinanomachi Campus, Keio University

Speaker：Nicolas Manel, PhD

Group Leader
INSERM Director of Research
Institut Curie, France

Title：Intracellular DNA Sensors: From Antiviral Immunity to Cancer Immunotherapy and Aging

Abstract：
Our research addresses the fundamental biological question of how organisms distinguish self from non-self. Following our initial work on HIV detection by intracellular innate immune sensors, our research has expanded to encompass broader mechanisms of nucleic acid sensing, particularly the cGAS-STING pathway, and their roles in viral infections, cancer, and aging, as well as their therapeutic potential. In this talk, I will present our latest advances in these areas.