Keio University Human Biology-Microbiome-Quantum Research Center (WPI-Bio2Q) held a seminar as follows.

Wednesday, 17:00 -18:00 September 3, 2025
Venue: 1F Lounge, Center for Integrated Medical Research, Shinanomachi Campus, Keio University

The 170th Brain Club Seminar – WPI-Bio2Q Open Seminar –
Host : Yuzaki Lab, Co-host : Bio2Q

Speaker:
Ryohei Yasuda, Ph.D.
Scientific Director, Neuroscience
Max Planck Florida Institute, USA

Title: “Decoding Synaptic Signaling Dynamics Underlying Plasticity”

Learning and memory depend on activity-dependent changes in synaptic strength and structure, yet the molecular mechanisms orchestrating these changes remain incompletely understood. These processes are mediated by complex biochemical signaling networks involving hundreds of intracellular and extracellular molecules operating on fine spatial and temporal scales. To dissect these networks, we have developed innovative imaging and optogenetic tools that allow visualization and perturbation of protein activity at individual synapses in freely behaving animals. These approaches have revealed how specific signaling events drive synaptic plasticity, modulate circuit function, and contribute to behavior, providing a new framework for understanding information storage in the brain.