EVENT
【Seminar Report】WPI-Bio2Q Open Seminar: Mark Travis, Ph.D.
August 13, 2025
Dr. Mark Travi
Credits: WPI-Bio2Q
Group Photo
Credits: WPI-Bio2Q
Poster
Credits: WPI-Bio2Q
Keio University Human Biology-Microbiome-Quantum Research Center (WPI-Bio2Q) held a seminar as follows.
Monday, 15:30 -16:30 July 28, 20252
Venue: Venue: Meeting Room 4, 4F Center for Integrated Medical Research, Shinanomachi Campus, Keio University
Speaker:
Mark Travis, Ph.D.
Professor of Immunology, Head of Division, Division of Immunology, Immunity to Infection and Respiratory Medicine, University of Manchester, UK
Title: “Regulation of mucosal immunity by integrins and TGF-beta”
Research Overview
Professor Travis’s research aims to elucidate the molecular and cellular mechanisms by which immune responses are maintained or disrupted in mucosal tissues such as the intestines and lungs. He analyzes the pathways that support homeostasis in healthy conditions and the processes by which invasions such as infection or radiation therapy disrupt the balance of the immune system and cause tissue damage, from both anatomical and functional perspectives.
Key Molecules and Pathways (TGF-β and Integrins)
The historical and central theme is the local activation of the cytokine TGF-β and its role in immune control. Specifically, the research has demonstrated that the activation of latent TGF-β by integrins is essential for inflammation suppression and mucosal immune homeostasis through regulatory T cells and dendritic cells. This includes discoveries such as autoimmune and colitis models, dendritic cell subsets, and preprocessing mechanisms for tissue-resident memory T cells.
More Bio2Q News
【7/17 Seminar】WPI-Bio2Q Open Seminar: Masari Watanabe, PhD & Yuansheng Zhao, PhD
Keio University Human Biology-Microbiome-Quantum Research Center (WPI-Bio2Q) will hold a seminar as follows. This is an event for faculty, ...
New Research Internship Student - Mr. Omar Moustafa Hassan Elatal
Introducing a New Research Internship Student of Bio2Q We are delighted to welcome Mr. Omar Moustafa Hassan Elatal as a Research Internship...
New Research Internship Student - Ms. Buse Nur Kiral
Introducing a new Research Internship Student of Bio2Q We are delighted to welcome Ms. Buse Nur Kiral as a Research Internship Student of B...
New Research Internship Student - Mr. Syed Ali Raza Naqvi
Introducing a new Research Internship Student of Bio2Q We are delighted to welcome Mr. Syed Ali Raza Naqvi as a Research Internship Student...
Event Report: The 3rd Bio2Q "LEAD50" Lecture with Ms. Yukako Uchinaga
On July 1, 2026, the Human Biology-Microbiome-Quantum Research Center (WPI-Bio2Q) at Keio University hosted the 3rd Bio2Q "LEAD50" Lecture a...

