RESEARCH
【Publication】Frustration-enhanced quantum annealing correction models with additional inter-replica interactions
October 26, 2026
Researchers from Bio2Q and Keio University have demonstrated that introducing additional interactions between copies of a quantum optimization problem can improve the performance of quantum annealers. By exploiting a phenomenon known as frustration, their approach enables more reliable identification of optimal solutions, even with short computation times and challenging energy conditions. These findings offer a promising strategy for improving the performance of near-term quantum computing technologies.
| Title | A conserved tyrosine motif encodes a structural vulnerability controlling stability and activity across J-domain proteins |
|---|---|
| Authors | Tomohiro Hattori 1 and Shu Tanaka 1,2,3,4,* |
| Short Description | Finding the best solution among a vast number of possibilities is a major challenge in many areas of science, including biology, where researchers must often analyze complex networks and interactions. Quantum annealing is a computing approach that uses principles of quantum physics to search for optimal solutions to these types of problems.
Researchers from Bio2Q and Keio University have demonstrated how introducing additional interactions between quantum systems can improve the ability of quantum annealers to solve complex optimization problems. However, the performance of quantum annealers is often limited by hardware noise, computational errors, and small energy gaps that make it difficult to reach the correct solution. To address these challenges, these researchers investigated quantum annealing correction methods that use multiple interconnected copies of a problem to improve solution accuracy. By introducing carefully designed interactions between these copies, including competing interactions that create a phenomenon known as frustration, they demonstrated that quantum annealers can identify optimal solutions even under conditions where conventional approaches struggle. Experiments on a real quantum annealer showed that these methods can achieve high success rates with shorter computation times by exploiting transitions between quantum states that are typically considered undesirable. These findings provide new insights into how quantum interactions can be used to overcome computational bottlenecks and establish a promising approach for improving the reliability and practical performance of near-term quantum computing technologies. |
| DOI | 10.1038/s42003-026-10947-w |
| Journal | Phys. Rev. |
| Vol/Num/Page |
A 114, 022470
|
| Publication Date | August 31, 2026 |
Affiliations
1 Graduate School of Science and Technology, Keio University, 3-14-1 Hiyoshi, Kohoku-ku, Yokohama-shi, Kanagawa 223-8522, Japan
2 Department of Applied Physics and Physico-Informatics, Keio University, 3-14-1 Hiyoshi, Kohoku-ku, Yokohama-shi, Kanagawa 223-8522, Japan
3 Keio University Sustainable Quantum Artificial Intelligence Center (KSQAIC), Keio University, Tokyo 108-8345, Japan
4 Human Biology-Microbiome-Quantum Research Center (WPI-Bio2Q), Keio University, Tokyo 108-8345, Japan
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