RESEARCH
[Publication] Centenarians have a diverse gut virome with the potential to modulate metabolism and promote healthy lifespan
September 4, 2023

Fig.1 | Tandem analysis of bacteria and viruses in centenarian microbiomes.
Title |
Centenarians have a diverse gut virome with the potential to modulate metabolism and promote healthy lifespan |
---|---|
Authors | Joachim Johansen [1],[2]; Koji Atarashi [3];, Yasumichi Arai [4]; Nobuyoshi Hirose [4]; Søren J. Sørensen [5]; Tommi Vatanen [1],[6]; Mikael Knip [6],[7],[8]; Kenya Honda [3]; Ramnik J. Xavier [1]; Simon Rasmussen [2],[9] & Damian R. Plichta [1] |
DOI | https://doi.org/10.1038/s41564-023-01370-6 |
Journal | Nature Microbiology |
Vol/Num/Page | 8, 1064-1078 |
Published Date | 15 May 2023 |
Affiliations:
[1] Infectious Disease and Microbiome Program, Broad Institute of MIT and Harvard, Cambridge, MA, USA.
[2] Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
[3] Department of Microbiology and Immunology, Keio University School of Medicine, Tokyo, Japan.
[4] Center for Supercentenarian Medical Research, Keio University School of Medicine, Tokyo, Japan.
[5] Section of Microbiology, Department of Biology, University of Copenhagen, Copenhagen, Denmark.
[6] Research Program for Clinical and Molecular Metabolism, Faculty of Medicine, University of Helsinki, Helsinki, Finland.
[7] New Children’s Hospital, Helsinki University Hospital, Helsinki, Finland.
[8] Tampere Center for Child Health Research, Tampere University Hospital, Tampere, Finland.
[9] The Novo Nordisk Foundation Center for Genomic Mechanisms of Disease, Broad Institute of MIT and Harvard, Cambridge, MA, USA.
More Bio2Q News
[Publication] Brain-wide mapping of immune receptors uncovers a neuromodulatory ...
This work reveals that immune molecules actively shape brain circuits, challenging the idea they only appear in disease and shedding light o...
[Publication] Emerging sensitivity to talking mouth in infants with low and elev...
This study shows that infants at higher risk for autism spectrum disorders pay less attention to talking mouths, a key cue for social develo...
[Publication] Microbiota-dependent modulation of intestinal anti-inflammatory CD...
This review, co-authored by a Bio2Q researcher, shows how gut microbes actively shape immunity and highlights new therapies like engineered ...
[Publication] Human Hepatocyte Organoids That Function Like the Real Thing
Bio2Q affiliated, Keio University, researchers have developed self-renewing human hepatocyte organoids that perform key liver functions and ...