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【研究成果】 Gut microbial carbohydrate metabolism contributes to insulin resistance

2023年10日3日

Extended Data Fig.1 | Overview of multi-omics analysis and data.

タイトル	Gut microbial carbohydrate metabolism contributes to insulin resistance
著者	Tadashi Takeuchi [1]; Tetsuya Kubota [1],[2],[3],[4],[5]; Yumiko Nakanishi [1],[2]; Hiroshi Tsugawa [6],[7],[8],[9]; Wataru Suda [10]; Andrew Tae-Jun Kwon [11]; Junshi Yazaki [12]; Kazutaka Ikeda [7],[13]; Shino Nemoto [1]; Yoshiki Mochizuki [12]; Toshimori Kitami [14]; Katsuyuki Yugi [15],[16],[17]; Yoshiko Mizuno [18],[19]; Nobutake Yamamichi [20]; Tsutomu Yamazaki [21]; Iseki Takamoto [3],[22]; Naoto Kubota [3]; Takashi Kadowaki [3],[23]; Erik Arner [11]; Piero Carninci [24],[25]; Osamu Ohara [12],[13]; Makoto Arita [7],[8],[26],[27]; Masahira Hattori [10]; Shigeo Koyasu [28] & Hiroshi Ohno [1],[2],[8]
DOI	https://doi.org/10.1038/s41586-023-06466-x
雑誌名	Nature
巻号ページ	volume 621, pages 389-395
出版年月日	2023年8月30日

Affiliations:
[1] Laboratory for Intestinal Ecosystem, RIKEN Center for Integrative Medical Sciences (IMS), Yokohama, Japan.
[2] Intestinal Microbiota Project, Kanagawa Institute of Industrial Science and Technology, Kawasaki, Japan.
[3] Department of Diabetes and Metabolic Diseases, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
[4] Division of Diabetes and Metabolism, The Institute for Medical Science Asahi Life Foundation, Tokyo, Japan.
[5] Department of Clinical Nutrition, National Institutes of Biomedical Innovation, Health and Nutrition (NIBIOHN), Tokyo, Japan.
[6] Metabolome Informatics Research Team, RIKEN Center for Sustainable Resource Science (CSRS), Yokohama, Japan.
[7] Laboratory for Metabolomics, RIKEN Center for Integrative Medical Sciences (IMS), Yokohama, Japan.
[8] Graduate School of Medical Life Science, Yokohama City University, Yokohama, Japan.
[9] Department of Biotechnology and Life Science, Tokyo University of Agriculture and Technology, Tokyo, Japan.
[10] Laboratory for Microbiome Sciences, RIKEN Center for Integrative Medical Sciences (IMS), Yokohama, Japan.
[11] Laboratory for Applied Regulatory Genomics Network Analysis, RIKEN Center for Integrative Medical Sciences (IMS), Yokohama, Japan.
[12] Laboratory for Integrative Genomics, RIKEN Center for Integrative Medical Sciences (IMS), Yokohama, Japan.
[13] Department of Applied Genomics, Kazusa DNA Research Institute, Kisarazu, Japan.
[14] Laboratory for Developmental Genetics, RIKEN Center for Integrative Medical Sciences (IMS), Yokohama, Japan.
[15] Laboratory for Integrated Cellular Systems, RIKEN Center for Integrative Medical Sciences (IMS), Yokohama, Japan.
[16] Institute for Advanced Biosciences, Keio University, Fujisawa, Japan.
[17] Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Tokyo, Japan.
[18] Department of Cardiovascular Medicine, The University of Tokyo, Tokyo, Japan.
[19] Development Bank of Japan, Tokyo, Japan.
[20] Center for Epidemiology and Preventive Medicine, The University of Tokyo Hospital, Tokyo, Japan.
[21] International University of Health and Welfare, Tokyo, Japan.
[22] Department of Metabolism and Endocrinology, Tokyo Medical University Ibaraki Medical Center, Ami Town, Japan.
[23] Toranomon Hospital, Tokyo, Japan.
[24] Laboratory for Transcriptome Technology, RIKEN Center for Integrative Medical Sciences (IMS), Yokohama, Japan.
[25] Fondazione Human Technopole, Milan, Italy.
[26] Division of Physiological Chemistry and Metabolism, Graduate School of Pharmaceutical Sciences, Keio University, Tokyo, Japan.
[27] Human Biology-Microbiome-Quantum Research Center (WPI-Bio2Q), Keio University, Tokyo, Japan.
[28] Laboratory for Immune Cell Systems, RIKEN Center for Integrative Medical Sciences (IMS), Yokohama, Japan.