NEWS

NEWS TYPE
RELEASE YEAR

RESEARCH

[Publication] Gut microbial carbohydrate metabolism contributes to insulin resistance

October 3, 2023

Title

Gut microbial carbohydrate metabolism contributes to insulin resistance

Authors

Tadashi Takeuchi [1]; Tetsuya Kubota [1],[2],[3],[4],[5]; Yumiko Nakanishi [1],[2]; Hiroshi Tsugawa [6],[7],[8],[9]; Wataru Suda [10]; Andrew Tae-Jun Kwon [11]; Junshi Yazaki [12]; Kazutaka Ikeda [7],[13]; Shino Nemoto [1]; Yoshiki Mochizuki [12]; Toshimori Kitami [14]; Katsuyuki Yugi [15],[16],[17]; Yoshiko Mizuno [18],[19]; Nobutake Yamamichi [20]; Tsutomu Yamazaki [21]; Iseki Takamoto [3],[22]; Naoto Kubota [3]; Takashi Kadowaki [3],[23]; Erik Arner [11]; Piero Carninci [24],[25]; Osamu Ohara [12],[13]; Makoto Arita [7],[8],[26],[27]; Masahira Hattori [10]; Shigeo Koyasu [28] & Hiroshi Ohno [1],[2],[8]

DOI https://doi.org/10.1038/s41586-023-06466-x
Journal Nature
Vol/Num/Page volume 621, pages 389-395
Published Date 30 August 2023

Affiliations:
[1] Laboratory for Intestinal Ecosystem, RIKEN Center for Integrative Medical Sciences (IMS), Yokohama, Japan.

[2] Intestinal Microbiota Project, Kanagawa Institute of Industrial Science and Technology, Kawasaki, Japan.
[3] Department of Diabetes and Metabolic Diseases, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
[4] Division of Diabetes and Metabolism, The Institute for Medical Science Asahi Life Foundation, Tokyo, Japan.
[5] Department of Clinical Nutrition, National Institutes of Biomedical Innovation, Health and Nutrition (NIBIOHN), Tokyo, Japan.
[6] Metabolome Informatics Research Team, RIKEN Center for Sustainable Resource Science (CSRS), Yokohama, Japan.
[7] Laboratory for Metabolomics, RIKEN Center for Integrative Medical Sciences (IMS), Yokohama, Japan.
[8] Graduate School of Medical Life Science, Yokohama City University, Yokohama, Japan.
[9] Department of Biotechnology and Life Science, Tokyo University of Agriculture and Technology, Tokyo, Japan.
[10] Laboratory for Microbiome Sciences, RIKEN Center for Integrative Medical Sciences (IMS), Yokohama, Japan.
[11] Laboratory for Applied Regulatory Genomics Network Analysis, RIKEN Center for Integrative Medical Sciences (IMS), Yokohama, Japan.
[12] Laboratory for Integrative Genomics, RIKEN Center for Integrative Medical Sciences (IMS), Yokohama, Japan.
[13] Department of Applied Genomics, Kazusa DNA Research Institute, Kisarazu, Japan.
[14] Laboratory for Developmental Genetics, RIKEN Center for Integrative Medical Sciences (IMS), Yokohama, Japan.
[15] Laboratory for Integrated Cellular Systems, RIKEN Center for Integrative Medical Sciences (IMS), Yokohama, Japan.
[16] Institute for Advanced Biosciences, Keio University, Fujisawa, Japan. 
[17] Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Tokyo, Japan.
[18] Department of Cardiovascular Medicine, The University of Tokyo, Tokyo, Japan.
[19] Development Bank of Japan, Tokyo, Japan.
[20] Center for Epidemiology and Preventive Medicine, The University of Tokyo Hospital, Tokyo, Japan.
[21] International University of Health and Welfare, Tokyo, Japan.
[22] Department of Metabolism and Endocrinology, Tokyo Medical University Ibaraki Medical Center, Ami Town, Japan.
[23] Toranomon Hospital, Tokyo, Japan.
[24] Laboratory for Transcriptome Technology, RIKEN Center for Integrative Medical Sciences (IMS), Yokohama, Japan.
[25] Fondazione Human Technopole, Milan, Italy.
[26] Division of Physiological Chemistry and Metabolism, Graduate School of Pharmaceutical Sciences, Keio University, Tokyo, Japan.
[27] Human Biology-Microbiome-Quantum Research Center (WPI-Bio2Q), Keio University, Tokyo, Japan.
[28] Laboratory for Immune Cell Systems, RIKEN Center for Integrative Medical Sciences (IMS), Yokohama, Japan.

 

More Bio2Q News

EVENT
2025.10.09

WPI-Bio2Q Social Event (2025.9.29)

WPI-Bio2Q held a social event at Keio University's Shinanomachi Campus. Date & Time: Monday, September 29, 2025, 12:00-13:00 Venue: ...

EVENT
2025.10.08

【Event】Keio Alumni Association Convention 2025

Keio University Human Biology-Microbiome-Quantum Research Center (WPI-Bio2Q) will give a presentation at the Keio Alumni Association Convent...

EVENT
2025.10.07

Visit to Bio2Q by Dr. Hitoshi Nakagama, President of the Japan Agency for Medica...

On September 22, 2025, Dr. Hitoshi Nakagama, President of the Japan Agency for Medical Research and Development (AMED), visited Bio2Q. Admi...

ANNOUNCEMENT
2025.10.02

Bio2Q Research Internship

The Keio University Human Biology-Microbiome-Quantum Research Center (WPI-Bio2Q) is offering a research internship as part of the STaMP prog...

ANNOUNCEMENT
2025.09.29

Newsletter “Bio2Q Connect” (Vol. 2, Issue 9)

We are delighted to share with you Vol. 2, Issue 9 of WPI-Bio2Q Newsletter “Bio2Q Connect”. Major topics of this issue include: Open S...