NEWS

NEWS TYPE
RELEASE YEAR

RESEARCH

[Publication] Diet-mediated constitutive induction of novel IL-4(+) ILC2 cells maintains intestinal homeostasis in mice

September 4, 2023

September 4, 2023

Graphical Abstract

Title

Diet-mediated constitutive induction of novel IL-4(+) ILC2 cells maintains intestinal homeostasis in mice
Authors Cui, Wanlin [1] , [9] ; Nagano, Yuji [2] , [3] ; Morita, Satoru [1] ; Tanoue, Takeshi [1] ; Yamane, Hidehiro [4] ; Ishikawa, Keiko [5] ; Sato, Toshiro [5] ; Kubo, Masato [2] , [7] ; Hori, Shohei [8] ; Taniguchi, Tadatsugu [3] , [6] ; Hatakeyama, Masanori [3] , [10] ; Atarashi, Koji [1] , [2] , [11] , [12] ; Honda, Kenya [1] , [2] , [12]
DOI https://doi.org/10.1084/jem.20221773
Journal Journal of Experimental Medicine
Vol/Num/Page Volume220 Issue8, e20221773
Published Date May 10 2023
Affiliation:
[1] Department of Microbiology and Immunology, School of Medicine, Keio University, Tokyo, Japan
[2] RIKEN Center for Integrative Medical Sciences (IMS), Yokohama, Japan
[3] Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
[4] Laboratory of Cellular and Molecular Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA
[5] Department of Organoid Medicine, Sakaguchi Laboratory, School of Medicine, Keio University, Tokyo, Japan
[6] Institute of Industrial Science, The University of Tokyo, Tokyo, Japan
[7] Division of Molecular Pathology, Research Institute for Biomedical Science, Tokyo University of Science, Noda, Japan
[8] Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan
[9] Department of Pediatrics, The First Hospital of China Medical University, Shenyang, China
[10] Institute of Microbial Chemistry (BIKAKEN), Microbial Chemistry Research Foundation, Tokyo, Japan
[11] Center of infection-associated cancer, Institute for Genetic Medicine, Hokkaido University, Sapporo, Japan
[12] Human Biology-Microbiome-Quantum Research Center (WPI-Bio2Q), Keio University, Tokyo, Japan

More Bio2Q News

EVENT
2025.07.31

【Seminar】WPI-Bio2Q Open Seminar: Shinichi Sunagawa, Ph.D.

Keio University Human Biology-Microbiome-Quantum Research Center (WPI-Bio2Q) will hold a seminar as follows. This is an event for faculty, ...

READ MORE
ANNOUNCEMENT
2025.07.29

Newsletter “Bio2Q Connect” (Vol. 2, Issue 8)

We are delighted to share with you Vol. 2, Issue 8 of WPI-Bio2Q Newsletter "Bio2Q Connect". Major topics of this issue include: Bio2Q ...

READ MORE
RESEARCH
2025.07.28

[Publication] Neuromodulation by the immune system: implications for brain-direc...

Co-authored by a Bio2Q researcher, this Review explores how the brain-immune axis acts as a key regulator of brain function and behavior thr...

READ MORE
EVENT
2025.07.24

【Seminar】WPI-Bio2Q Open Seminar: Kazuki Nagashima, MD-PhD

Keio University Human Biology-Microbiome-Quantum Research Center (WPI-Bio2Q) will hold a seminar as follows. This is an event for faculty, ...

READ MORE
RESEARCH
2025.07.22

[Publication] Mammalian Tolerance to Amino Acid Heterochirality

Co-authored by Bio2Q and Keio University researchers, this Review explores the role of D-amino acids in mammals, highlighting their function...

READ MORE