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Subtle-seq reveals frequent ageing-associated chromosome fragmentation on nucleosome core DNA

Matsubara R, Solberg T, Nowacki M. Nucleic Acids Res.  2026 April 13; 54(7):gkag298. doi:10.1093/nar/gkag298

Unbinned contigs expand known diversity in the global microbiome

Prasoodanan Pk V, Maistrenko OM, Fullam A, Mende DR, Kartal E, Coelho LP, Spang A, Bork P, Schmidt TSB. Nat Microbiol.  2026 April 3; 11(5):1437-1449. doi:10.1038/s41564-026-02314-6

Mitochondria-targeting ACSL6 variant drives mitochondrial fragmentation potentially through local DHA-CoA production

Ota R, Isobe Y, Ohba Y, Arita M. Sci Rep.  2026 April 1; 16(1):15456. doi:10.1038/s41598-026-46977-x

Optimization of lens size and ion source parameters for gas chromatography/mass spectrometry-based metabolomics using hydrogen as a carrier gas

Sato M, Hayasaka R, Soga T, Hirayama A. J Chromatogr A.  2026 March 28; 1776:466945. doi:10.1016/j.chroma.2026.466945

Gut Commensal Klebsiella pneumoniae Extracellular Vesicles Shape a Liver Microenvironment Conducive to Gut-Liver Bacterial Translocation and Pro-Tumorigenic Processes

Tsubaki S, Nashimoto S, Tanaka R, Toyomoto T, Tsutsuki H, Kato K, Nakayama J, Kimura K, Oshima K, Yamamoto Y, Okusaka T, Esaki M, Kawai N, Ota N, Yoshioka Y, Ochiya T, Saito Y, Sawa T, Hozumi K, Matsuzaki J, Tsugawa H. J Extracell Vesicles.  2026 March 26; 15(4):e70262. doi:10.1002/jev2.70262

SMASH Imaging: A Serial Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry Strategy for High-Resolution Imaging Facilitates Dual-Polarity and MS2 Spatial Lipidomics on a Single Tissue Section

Uchino H, Tsugawa H, Arita M. Anal Chem.  2026 March 26; 98(13):9540-9554. doi:10.1021/acs.analchem.5c03738

Polypharmacologic phosphoinositide modulation by FTY720 triggers endomembrane trafficking collapse and metabolic starvation in cancer cells

Kofuji S, Sumita K, Ikeda Y, Takahashi Y, Tabata S, Ito D, Hirota Y, Sasaki M, Kanoh H, Nakatsu F, Takeuchi K, Senda T, Davis MI, Shen M, Wakimoto H, Hirayama A, Soga T, Simeonov A, Sasaki AT. Biochem Biophys Res Commun.  2026 March 24; 815:153671. doi:10.1016/j.bbrc.2026.153671

Development of a Self-Adjuvanting Influenza Peptide-Glycolipid Conjugate Inducing CD8(+) T-Cell Immunity

Kikuchi S, Ogura H, Matsumaru T, Ishido S, Fujimoto Y. Chembiochem.  2026 March 13; 27(5):e202500979. doi:10.1002/cbic.202500979

Elevated glucose metabolism via the hexosamine biosynthesis pathway: A metabolic signature of high-fluorodeoxyglucose-uptake lung adenocarcinoma

Watanabe H, Makinoshima H, Kanauchi N, Kabasawa T, Suzuki J, Takamori S, Sasage T, Abe K, Hoshijima K, Uchida T, Soga T, Shiono S. Surg Today.  2026 March 10; 56(8):1645-1656. doi:10.1007/s00595-026-03276-2

Unique ecology of co-occurring functionally and phylogenetically undescribed species in the infant oral microbiome

Pucci N, Kaan AM, Ujčič-Voortman J, Verhoeff AP, Zaura E, Mende DR. PLoS Comput Biol.  2026 March 5; 22(3):e1013185. doi:10.1371/journal.pcbi.1013185

Microbiota-mediated induction of beige adipocytes in response to dietary cues

Tanoue T, Nagayama M, Roochana AJA, Zimmerman S, Ashenberg O, Jain T, Igarashi R, Sasajima S, Takeshita K, Hetherington N, Okahashi N, Ueda M, Konishi M, Nakayama Y, Minoda A, Skelly AN, Minokoshi Y, Pucci N, Mende DR, Arita M, Yamamoto H, Watanabe S, Miura K, Behie SW, Suda W, Sato T. Atarashi K, Matsushita M, Kajimura S, Plichta DR, Saito M, Xavier RJ, Honda K. Nature.  2026 March 4; 653(8114). doi:10.1038/s41586-026-10205-3

Global loss of metabolic responsiveness and elevated enzyme in leptin deficient obese mice during starvation

Li D, Morita K, Kokaji T, Hatano A, Hirayama A, Soga T, Suzuki Y, Matsumoto M, Tsuchiya T, Ozaki H, Ohno S, Inoue H, Inaba Y, Maehara H, Sugimoto H, Pan Y, Kuroda S. NPJ Syst Biol Appl.  2026 March 3; 12(1):53. doi:10.1038/s41540-026-00678-3

Scientific mobility in microbiology - 14

Sahayasheela VJ. Trends Microbiol.  2026 March; 34(3):224-227. doi:10.1016/j.tim.2026.01.005

Live-Cell Imaging Analysis of the Intracellular Behavior of the C-Type Lectin Receptor Mincle and Its Ligand Using Newly Developed Fluorescence-Labeled Molecular Probes Based on Trehalose Diester

Matsumaru T, Okubo K, Takayama J, Hirano Y, Huo YR, Toguchi S, Yoshida K, Fujii A, Suzuki T, Lin CC, Dohmae N, Yamasaki S, Fujimoto Y. ACS Chem Biol.  2026 February 16; 21(3):519-526. doi:10.1021/acschembio.5c00794

Overcoming phagocytosis resistance of hypervirulent Klebsiella pneumoniae by directly targeting capsules

Tsubaki S, Toyomoto T, Tanaka R, Imai J, Matsuzaki J, Hozumi K, Tsugawa H. Microb Cell.  2026 February 16; 21(3):519-526. doi:10.1021/acschembio.5c00794