世界トップレベル研究拠点（WPI）慶應義塾大学ヒト生物学-微生物叢-量子計算研究センター(Bio2Q)は以下のとおり公開セミナーを開催しました。

日時：2026年10月6日（火）17:00-18:00

会場：慶應義塾大学 信濃町キャンパス 総合医科学研究棟 1階 ラウンジ

講演者：Chun-Jun Guo, PhD
Associate Professor
Department of Microbiology ＆Immunology
Weill Cornell Medicine

演題：Using Genetics to Explore Microbe-Host Interactions at the Molecular Level

要旨：
The gut microbiota profoundly influences human physiology and disease through the production of diverse bioactive small molecules. However, the specific microbial pathways and molecular mechanisms that mediate these effects remain poorly defined. Elucidating these causal relationships is essential for developing strategies to monitor, predict, and therapeutically manipulate the microbiota to promote human health and treat disease. Here, we present our recent progress in developing genetic tools for non-model gut commensals and applying these toolsets to define how microbiota-encoded metabolic pathways and their metabolites regulate host immunity in cancer and inflammatory bowel disease. Together, these studies establish mechanistic links between microbial metabolism and host immune regulation and reveal new opportunities to leverage microbiota-derived metabolites as biomarkers, therapeutic targets, and adjuvants to improve the treatment of cancer and IBD.