NEWS

NEWS TYPE
RELEASE YEAR

RESEARCH

[Publication] Emerging sensitivity to talking mouth in infants with low and elevated likelihood of autism spectrum disorder: A longitudinal study

July 11, 2025

This study shows that infants at higher risk for autism spectrum disorders pay less attention to talking mouths, a key cue for social development, offering a non-invasive early detection method.

Title Emerging sensitivity to talking mouth in infants with low and elevated likelihood of autism spectrum disorder: A longitudinal study
Authors
Masahiro Hata [1] , Mingdi Xu [1], Yoko Hakuno [1], Eriko Yamamoto [2] & Yasuyo Minagawa [1], [2],[3]
Short Description How Early Visual Attention May Signal Autism Risk
This longitudinal study explores how infants, both with low and elevated likelihoods of autism spectrum disorder (ASD), respond to talking faces during their first year of life. Using eye-tracking technology, Bio2Q researchers uncovered an interesting pattern, that is while most infants increasingly focus on a talking mouth between 6 and 12 months of age, those with a higher likelihood of ASD show reduced sensitivity to this developmental shift. These findings suggest that attention to a talking mouth may serve as a critical cue for typical social and language development. This work enhances our understanding of early autism detection by providing a non-invasive way by which to identify behavioral differences, well before clinical symptoms arise.
DOI https://doi.org/10.1016/j.infbeh.2025.102057
Journal Infant Behavior and Development
Vol/Num/Page Article 102057
Publication Date Published online: 2025 April 16.

Affiliations:
[1] Center for Design of Future Symbiosis, Keio University Global Research Institute, Tokyo, Japan
[2] Department of Psychology, Graduate School of Human Relations, Keio University, Tokyo, Japan
[3] Human Biology-Microbiome-Quantum Research Center (WPI-Bio2Q), Keio University, Tokyo, Japan

More Bio2Q News

ANNOUNCEMENT
2025.12.24

【Seminar】 WPI-Bio2Q Open Seminar: Tomoe Ishikawa, Ph.D.(for Keio Members)

Keio University Human Biology-Microbiome-Quantum Research Center (WPI-Bio2Q) will hold a seminar as follows. This event is only for faculty...

ANNOUNCEMENT
2025.12.22

OPEN CALL: Technical Staff (Animal Experiments)

The Bio2Q Open Lab invites applications for a proactive, highly organized, and safety-conscious lab technician with hands-on experience in a...

EVENT
2025.12.19

WPI-Bio2Q Social Event (2025.12.19)

WPI-Bio2Q held a social event at Keio University’s Shinanomachi Campus. Date & Time: Friday, December 19, 2025 Venue: Bio2Q Open Lab...

ANNOUNCEMENT
2025.12.19

Research Internship Program 2026(Period 2)

Bio2Q is now offering a research internship opportunity as part of STaMP, a joint cross-disciplinary graduate English program for students i...

EVENT
2025.12.18

【1/7 Seminar】WPI-Bio2Q Open Seminar: Masahiro Kanai, PhD

Keio University Human Biology-Microbiome-Quantum Research Center (WPI-Bio2Q) will hold a seminar as follows. This is an event for faculty...