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研究

【研究成果】Commensal consortia decolonize Enterobacteriaceae via ecological control

2024年9日19日

Fig.1: Elaboration of an 18-strain-consortium capable of decolonizing Klebsiella.

タイトル	Commensal consortia decolonize Enterobacteriaceae via ecological control
著者	Munehiro Furuichi [1],[2],[14]; Takaaki Kawaguchi [1],[2],[14]; Marie-Madlen Pust [3],[4],[14]; Keiko Yasuma-Mitobe [1],[14]; Damian R. Plichta [3]; Naomi Hasegawa [1]; Takashi Ohya [1],[2]; Shakti K. Bhattarai [5]; Satoshi Sasajima [1]; Yoshimasa Aoto [6]; Timur Tuganbaev [1],[7]; Mizuki Yaginuma [1]; Masahiro Ueda [2],[6]; Nobuyuki Okahashi [2],[8],[9]; Kimiko Amafuji [6]; Yuko Kiridoshi [6]; Kayoko Sugita [1]; Martin Stražar [3]; Julian Avila-Pacheco [3]; Kerry Pierce [3]; Clary B. Clish [3]; Ashwin N. Skelly [1]; Masahira Hattori [2],[10]; Nobuhiro Nakamoto [11]; Silvia Caballero [12]; Jason M. Norman [12]; Bernat Olle [12]; Takeshi Tanoue [1],[2]; Wataru Suda [2],[10]; Makoto Arita [2],[7],[9]; Vanni Bucci [5]; Koji Atarashi [1],[2],[7]; Ramnik J. Xavier [3],[4],[13] & Kenya Honda [1],[2],[7]
DOI	https://doi.org/10.1038/s41586-024-07960-6
雑誌名	Nature
巻号	633, 878–886 (2024)
出版年月日	2024年9月18日

Affiliations:
[1] Department of Microbiology and Immunology, Keio University School of Medicine, Tokyo, Japan.
[2] RIKEN Center for Integrative Medical Sciences, Yokohama, Japan.
[3] Infectious Disease and Microbiome Program, Broad Institute of MIT and Harvard, Cambridge, MA, USA.
[4] Center for Computational and Integrative Biology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
[5] Department of Microbiology and Physiological Systems, Program in Microbiome Dynamics, UMass Chan Medical School, Worcester, MA, USA.
[6] JSR-Keio University Medical and Chemical Innovation Center, Keio University School of Medicine, Tokyo, Japan.
[7] Human Biology Microbiome Quantum Research Center (Bio2Q), Keio University, Tokyo, Japan.
[8] Department of Bioinformatic Engineering, Graduate School of Information Science and Technology, Osaka University, Osaka, Japan.
[9] Division of Physiological Chemistry and Metabolism, Graduate School of Pharmaceutical Sciences, Keio University, Tokyo, Japan.
[10] Cooperative Major in Advanced Health Science, Graduate School of Advanced Science and Engineering, Waseda University, Tokyo, Japan.
[11] Division of Gastroenterology and Hepatology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan.
[12] Vedanta Biosciences, Cambridge, MA, USA.
[13] Department of Molecular Biology, Massachusetts General Hospital, Boston, MA, USA.
[14] These authors contributed equally: Munehiro Furuichi, Takaaki Kawaguchi, Marie-Madlen Pust, Keiko Yasuma-Mitobe.